| Higgins, Melanie A.; Tegl, Gregor; MacDonald, Spencer S.; Arnal, Gregory; Brumer, Harry et al. (2021). N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes. ACS Chemical Biology 16(4) . 10.1021/acschembio.0c00995. [PDB: 7lqx, 7lr1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Huang, Ji; Fraser, Marie E. (2021). Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase. Acta Crystallographica Section D: Structural Biology 77(3) , 357-368. 10.1107/s2059798321000334. [PDB: 7jj0, 7jkr] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Langston, Steven P.; Grossman, Stephen; England, Dylan; Afroze, Roushan; Bence, Neil et al. (2021). Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01491. [PDB: 6xog, 6xoh] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Liang, J.; Naineni, S.K.; Pelletier, J.; Nagar, B. (2021). Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog. Protein Data Bank: 6xki. |
CMCF-ID |
PDB Deposition |
Health |
| Lin, Chang Sheng-Huei; Chan, Anson C.K.; Vermeulen, Jenny; Brockerman, Jacob; Soni, Arvind S. et al. (2021). Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni. Journal of Biological Chemistry 296, 100528. 10.1016/j.jbc.2021.100528. [PDB: 6xj7] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Lin, C.S.; Chan, A.C.; Murphy, M.E. (2021). Crystal structure of the helical cell shape determining protein Pgp2 (K307A mutant) from Campylobacter jejuni. Protein Data Bank: 6xj7. |
CMCF-BM |
PDB Deposition |
Health |
| Li, Z.; Rini, J.M. (2021). SARS-CoV-2 RBD in complex with Fab 15033. Protein Data Bank: 7klg. |
CMCF-BM |
PDB Deposition |
Health |
| Li, Z.; Rini, J.M. (2021). SARS-CoV-2 RBD in complex with Fab 15033-7. Protein Data Bank: 7klh. |
CMCF-BM |
PDB Deposition |
Health |
| Lyons, B.; Lidster, T.; Merrill, A.R. (2021). Scabin (S117A) toxin from Streptomyces scabies. Protein Data Bank: 6vuv. |
CMCF-ID |
PDB Deposition |
Health |
| Majewski, Dorothy D.; Okon, Mark; Heinkel, Florian; Robb, Craig S.; Vuckovic, Marija et al. (2021). Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure 29(2) . 10.1016/j.str.2020.08.006. [PDB: 6xfj] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Mulligan, Vikram Khipple; Workman, Sean; Sun, Tianjun; Rettie, Stephen; Li, Xinting et al. (2021). Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1. Proceedings of the National Academy of Sciences of the United States of America 118(12) , e2012800118. 10.1073/pnas.2012800118. [PDB: 6xbe, 6xbf] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Murray, J.M. (2021). BRD4-BD1 Compound6 (methyl 4-(3,5-difluoropyridin-2-yl)-10-methyl-7-((methylsulfonyl)methyl)-11-oxo-3,4,10,11-tetrahydro-1H-1,4,10-triazadibenzo[cd,f]azulene-6-carboxylate). Protein Data Bank: 7khl. |
CMCF-ID |
PDB Deposition |
Health |
| Payandeh, J.; Ho, H. (2021). Fab CJ11 in complex IL-1beta peptide liberated by Caspase cleavage. Protein Data Bank: 7jwq. |
CMCF-ID |
PDB Deposition |
Health |
| Quiroz, Ryan V.; Reutershan, Michael H.; Schneider, Sebastian E.; Sloman, David; Lacey, Brian M. et al. (2021). The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. Journal of Medicinal Chemistry 64(7) , 3911-3939. 10.1021/acs.jmedchem.0c02083. [PDB: 7kib] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Rathinaswamy, Manoj K; Gaieb, Zied; Fleming, Kaelin D; Borsari, Chiara; Harris, Noah J et al. (2021). Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors. eLife 10. 10.7554/elife.64691. [PDB: 7jwe, 7jwz, 7jx0] |
CMCF-ID |
Peer-Reviewed Article |
Health |