Publication Beamlines Strategic Pillar
Keylor, Mitchell H.; Gulati, Anmol; Kattar, Solomon D.; Johnson, Rebecca E.; Chau, Ryan W. et al. (2021). Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors. Journal of Medicinal Chemistry 65(1) , 838-856. 10.1021/acs.jmedchem.1c01968. [PDB: 7suh] CMCF-ID Health
Kimber, M.S.; Forrester, T.J.B. (2021). Cannabis sativa bibenzyl synthase. Protein Data Bank: 7sgy. CMCF-ID Agriculture
Liu, Weifeng; Maben, Zachary; Wang, Carole; Lindquist, Kevin C.; Li, Manqing et al. (2021). Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex. Journal of Biological Chemistry 297(4) , 101102. 10.1016/j.jbc.2021.101102. [PDB: 7kx0] CMCF-ID Health
Murray, B.W.; Rogers, E.; Zhai, D.; Deng, W.; Chen, X. et al. (2021). Crystal structure of TrkA kinase with repotrectinib. Protein Data Bank: 7vko. CMCF-ID Health
Nasu, Yusuke; Murphy-Royal, Ciaran; Wen, Yurong; Haidey, Jordan N.; Molina, Rosana S. et al. (2021). A genetically encoded fluorescent biosensor for extracellular l-lactate. Nature Communications 12(1) . 10.1038/s41467-021-27332-2. [PDB: 7e9y] CMCF-ID Health
Nilvebrant, Johan; Ereño-Orbea, June; Gorelik, Maryna; Julian, Mark C.; Tessier, Peter M. et al. (2021). Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains. Journal of Molecular Biology 433(21) , 167241. 10.1016/j.jmb.2021.167241. [PDB: 7ooi] CMCF-ID Health
Pham, N. T. Hang; Létourneau, Myriam; Fortier, Marlène; Bégin, Gabriel; Al-Abdul-Wahid, M. Sameer et al. (2021). Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7. Journal of Biological Chemistry 297(5) , 101308. 10.1016/j.jbc.2021.101308. [PDB: 6vtp, 6vtr] CMCF-BM Health
Rasool, S.; Veyron, S.; Trempe, J.F. (2021). Crystal structure of the cytosolic domain of Tribolium castaneum PINK1 phosphorylated at Ser205 in complex with ADP analog. Protein Data Bank: 7mp9. CMCF-ID Health
Rasool, S.; Veyron, S.; Trempe, J.F. (2021). Crystal structure of the cytosolic domain of Tribolium castaneum PINK1 in the non-phosphorylated state. Protein Data Bank: 7mp8. CMCF-ID Health
Sahtout, N.; Kuttiyatveetil, J.R.A.; Sanders, D.A.R. (2021). Structure of thioredoxin reductase from the thermophilic eubacterium Thermosipho africanus TCF52B. Protein Data Bank: 7jyp. CMCF-ID Health
Saran, S.; Majdi Yazdi, M.; Sanders, D.A.R. (2021). Dihydrodipicolinate synthase (DHDPS) from C.jejuni, E88D mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site. Protein Data Bank: 7ko3. CMCF-ID Health
Saran, S.; Majdi Yazdi, M.; Sanders, D.A.R. (2021). Dihydrodipicolinate synthase (DHDPS) from C.jejuni, E88D mutant with pyruvate bound in the active site. Protein Data Bank: 7ko1. CMCF-ID Health
Saran, S.; Majdi Yazdi, M.; Sanders, D.A.R. (2021). Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59N mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site. Protein Data Bank: 7km1. CMCF-ID Health
Saran, S.; Majdi Yazdi, M.; Sanders, D.A.R. (2021). Dihydrodipicolinate synthase (DHDPS) from C.jejuni, N84D mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site. Protein Data Bank: 7kkt. CMCF-ID Health
Saran, S.; Majdi Yazdi, M.; Sanders, D.A.R. (2021). Dihydrodipicolinate synthase (DHDPS) from C.jejuni, N84D mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site. Protein Data Bank: 7kkg. CMCF-ID Health