Worrall, L.J.; Sobhanifar, S.; King, D.T.; Strynadka, N.C. (2017). Crystal structure of S. aureus TarS 1-349 in complex with UDP-GlcNAc. Protein Data Bank: 5tzj. |
CMCF-ID |
PDB Deposition |
Health |
Worrall, L.J.; Sobhanifar, S.; King, D.T.; Strynadka, N.C. (2017). Crystal structure of S. aureus TarS 1-349. Protein Data Bank: 5tzi. |
CMCF-ID |
PDB Deposition |
Health |
Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E. et al. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. [PDB: 5u79, 5u7b, 5u7c, 5u82, 5u83] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Stanger, Frédéric V.; de Beer, Tjaart A.P.; Dranow, David M.; Schirmer, Tilman; Phan, Isabelle et al. (2017). The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook. Structure 25(1) , 203-211. 10.1016/j.str.2016.10.010. [PDB: 4yk1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4721 1-(4-fluorophenyl)-1H-imidazole. Protein Data Bank: 5ifd. |
CMCF-ID |
PDB Deposition |
Health |
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-2643 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine. Protein Data Bank: 5if8. |
CMCF-ID |
PDB Deposition |
Health |
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4720 1-(4-bromophenyl)-1H-imidazole. Protein Data Bank: 5ifc. |
CMCF-ID |
PDB Deposition |
Health |
Randriamihaja, Antsa (2017). Structural analyses of the ecto-nucleotides pyrophosphatases/phosphodiesterases 3 and 5. Supervisor: Nagar, Bhushan. QC, Canada: McGill University. https://escholarship.mcgill.ca/concern/theses/td96k517j. |
CMCF-ID |
Masters Thesis |
Health |
Planken, Simon; Behenna, Douglas C.; Nair, Sajiv K.; Johnson, Theodore O.; Nagata, Asako et al. (2017). Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR. Journal of Medicinal Chemistry 60(7) , 3002-3019. 10.1021/acs.jmedchem.6b01894. [PDB: 5ugc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Park, J.; Zielinski, M.; Tsantrizos, Y.S.; Berghuis, A.M. (2017). Crystal structure of human FPPS with allosterically bound FPP. Protein Data Bank: 5ja0. |
CMCF-ID |
PDB Deposition |
Health |
Park, J.; Magder, A.; Leung, C.Y.; Tsantrizos, Y.S.; Berghuis, A.M. et al. (2017). Crystal structure of human FPPS in complex with an allosteric inhibitor CL-06-057. Protein Data Bank: 5juz. |
CMCF-ID |
PDB Deposition |
Health |
Park, J.; Leung, C.Y.; Tsantrizos, Y.S.; Berghuis, A.M. (2017). Crystal structure of human FPPS in complex with an allosteric inhibitor CL-08-066. Protein Data Bank: 5jv1. |
CMCF-ID |
PDB Deposition |
Health |
Park, Jaeok; Zielinski, Michal; Magder, Alexandr; Tsantrizos, Youla S.; Berghuis, Albert M. et al. (2017). Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Communications 8(1) . 10.1038/ncomms14132. [PDB: 5ja0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Park, Jaeok; Leung, Chun Yuen; Matralis, Alexios N.; Lacbay, Cyrus M.; Tsakos, Michail et al. (2017). Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. Journal of Medicinal Chemistry 60(5) , 2119-2134. 10.1021/acs.jmedchem.6b01888. [PDB: 5juz, 5jv1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L. et al. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences of the United States of America 114(5) , E679-E688. 10.1073/pnas.1615141114. [PDB: 5kd5, 5kd8, 5kdn, 5kdu, 5kdv, 5kdw, 5kdx] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |