Publication Beamlines Strategic Pillar
Langston, Steven P.; Grossman, Stephen; England, Dylan; Afroze, Roushan; Bence, Neil et al. (2021). Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01491. [PDB: 6xog, 6xoh] CMCF-ID Health
Huang, Ji; Fraser, Marie E. (2021). Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase. Acta Crystallographica Section D: Structural Biology 77(3) , 357-368. 10.1107/s2059798321000334. [PDB: 7jj0, 7jkr] CMCF-ID Health
Dragovich, Peter S.; Pillow, Thomas H.; Blake, Robert A.; Sadowsky, Jack D.; Adaligil, Emel et al. (2021). Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01846. [PDB: 7khl] CMCF-ID Health
Scholl, Connor L.; Tsuda, Sakae; Graham, Laurie A.; Davies, Peter L. (2021). Crystal waters on the nine polyproline type II helical bundle springtail antifreeze protein from Granisotoma rainieri match the ice lattice. FEBS Journal 288(14) . 10.1111/febs.15717. [PDB: 7jjv] CMCF-ID Health
Vatta, Maritza; Lyons, Bronwyn; Heney, Kayla A.; Lidster, Taylor; Merrill, A. Rod et al. (2021). Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies. Toxins 13(1) , 55. 10.3390/toxins13010055. [PDB: 6vuv, 6vv4, 6vvf] CMCF-ID Health
Chen, Shuo; Wu, Jia-Le; Liang, Ying; Tang, Yi-Gang; Song, Hua-Xin et al. (2021). Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site. Cancer Cell 39(2) . 10.1016/j.ccell.2020.11.013. [PDB: 7dhz] CMCF-ID Health
Majewski, Dorothy D.; Okon, Mark; Heinkel, Florian; Robb, Craig S.; Vuckovic, Marija et al. (2021). Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure 29(2) . 10.1016/j.str.2020.08.006. [PDB: 6xfj] CMCF-BM, CMCF-ID Health
Guo, Amin; Zhang, Jianhua; Wang, Yufei; Fan, Jiadong; He, Bo et al. (2021). Nanoscale Detection of Subcellular Nanoparticles by X-Ray Diffraction Imaging for Precise Quantitative Analysis of Whole Cancer Cells. Analytical Chemistry 93(12) , 5201-5210. 10.1021/acs.analchem.0c05282. SM Health
Lin, C.S.; Chan, A.C.; Murphy, M.E. (2021). Crystal structure of the helical cell shape determining protein Pgp2 (K307A mutant) from Campylobacter jejuni. Protein Data Bank: 6xj7. CMCF-BM Health
Zielinski, M.; Berghuis, A.M. (2021). Erythromycin esterase mutant EreC H289N in its open conformation. Protein Data Bank: 6xcs. CMCF-BM Health
Li, Z.; Rini, J.M. (2021). SARS-CoV-2 RBD in complex with Fab 15033. Protein Data Bank: 7klg. CMCF-BM Health
Li, Z.; Rini, J.M. (2021). SARS-CoV-2 RBD in complex with Fab 15033-7. Protein Data Bank: 7klh. CMCF-BM Health
Gerak, C.A.N.; Kolesnikov, M.; Murphy, M.E.P.; McIntosh, L.P. (2021). Crystal structure of the monomeric ETV6 PNT domain. Protein Data Bank: 7ju2. CMCF-BM Health
Worrall, L.J.; Sun, T.; Mulligan, V.K.; Strynadka, N.C.J. (2021). Structure of NDM-1 in complex with macrocycle inhibitor NDM1i-1G. Protein Data Bank: 6xbf. CMCF-ID Health
Worrall, L.J.; Sun, T.; Mulligan, V.K.; Strynadka, N.C.J. (2021). Structure of NDM-1 in complex with macrocycle inhibitor NDM1i-1F. Protein Data Bank: 6xbe. CMCF-ID Health