Publication Beamlines Strategic Pillar
Park, Jaeok; Zielinski, Michal; Magder, Alexandr; Tsantrizos, Youla S.; Berghuis, Albert M. et al. (2017). Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Communications 8(1) . 10.1038/ncomms14132. [PDB: 5ja0] CMCF-ID Health
Planken, Simon; Behenna, Douglas C.; Nair, Sajiv K.; Johnson, Theodore O.; Nagata, Asako et al. (2017). Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR. Journal of Medicinal Chemistry 60(7) , 3002-3019. 10.1021/acs.jmedchem.6b01894. [PDB: 5ugc] CMCF-ID Health
Pratt, Isaac Vorster; Cooper, David Michael Lane (2017). A method for measuring the three-dimensional orientation of cortical canals with implications for comparative analysis of bone microstructure in vertebrates. Micron 92, 32-38. 10.1016/j.micron.2016.10.006. BMIT-ID Health
Stanger, Frédéric V.; de Beer, Tjaart A.P.; Dranow, David M.; Schirmer, Tilman; Phan, Isabelle et al. (2017). The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook. Structure 25(1) , 203-211. 10.1016/j.str.2016.10.010. [PDB: 4yk1] CMCF-ID Health
Ulaganathan, ThirumalaiSelvi; Boniecki, Michal T.; Foran, Elizabeth; Buravenkov, Vitaliy; Mizrachi, Naama et al. (2017). New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture. ACS Chemical Biology 12(5) , 1269-1280. 10.1021/acschembio.7b00126. [PDB: 5uam, 5uas] CMCF-BM Health
Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E. et al. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. [PDB: 5u79, 5u7b, 5u7c, 5u82, 5u83] CMCF-ID Health
Williamson, Michael R.; Dietrich, Kristen; Hackett, Mark J.; Caine, Sally; Nadeau, Colby A. et al. (2017). Rehabilitation Augments Hematoma Clearance and Attenuates Oxidative Injury and Ion Dyshomeostasis After Brain Hemorrhage. Stroke 48(1) , 195-203. 10.1161/strokeaha.116.015404. MID-IR Health
Randriamihaja, Antsa (2017). Structural analyses of the ecto-nucleotides pyrophosphatases/phosphodiesterases 3 and 5. Supervisor: Nagar, Bhushan. QC, Canada: McGill University. https://escholarship.mcgill.ca/concern/theses/td96k517j. CMCF-ID Health
Kodandaram Pillarisetti; Eric Thomas Baldwin; Gordon D. Powers; Rosa Maria Fernandes Cardoso; Ricardo Attar et al. (2017). Anti-BCMA Antibodies, Bispecific Antigen Binding Molecules that Bind BCMA and CD3, and Uses Thereof. Patent Number: US20170051068A1. CMCF-ID Health
Kodandaram Pillarisetti; Eric Thomas BALDWIN; Gordon D. Powers; Rosa Maria Fernandes CARDOSO; Ricardo Attar et al. (2017). Anti-bcma antibodies, bispecific antigen binding molecules that bind bcma and cd3, and uses thereof. Patent Number: WO2017031104A1. CMCF-ID Health
Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 N216A monomeric mutant (L457E/L464E) with m7Gppp-AAAA (anti conformation of cap). Protein Data Bank: 5udl. CMCF-ID Health
Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 monomeric mutant (L457E/L464E) with PPP-AAAA. Protein Data Bank: 5udk. CMCF-ID Health
Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 monomeric mutant (L457E/L464E) with Gppp-AAAA. Protein Data Bank: 5udj. CMCF-ID Health
Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 monomeric mutant (L457E/L464E) with m7Gppp-AAAA (syn and anti conformations of cap). Protein Data Bank: 5udi. CMCF-ID Health
Arya, T.; Sharifahmadian, M.; Sygusch, J.; Baron, B. (2017). Conformational changes during monomer-to-dimer transition of Brucella suis VirB8. Protein Data Bank: 5jbs. CMCF-ID Health