Publication Beamlines Strategic Pillar
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Brooks, Cory L.; MacKenzie, C. Roger; Caveney, Nathanael et al. (2018). Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody–Carbohydrate Binding Affinity by an Order of Magnitude. Biochemistry 58(6) , 714-726. 10.1021/acs.biochem.8b00318. [PDB: 6c5h, 6c5i, 6c5j, 6c5k] CMCF-ID Health
Hamaguchi, Hisao; Amano, Yasushi; Moritomo, Ayako; Shirakami, Shohei; Nakajima, Yutaka et al. (2018). Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor. Bioorganic and Medicinal Chemistry 26(18) , 4971-4983. 10.1016/j.bmc.2018.08.005. [PDB: 6aak] CMCF-ID Health
Hedges, Jason B.; Kuatsjah, Eugene; Du, Yi-Ling; Eltis, Lindsay D.; Ryan, Katherine S. et al. (2018). Snapshots of the Catalytic Cycle of an O2, Pyridoxal Phosphate-Dependent Hydroxylase. ACS Chemical Biology 13(4) , 965-974. 10.1021/acschembio.8b00039. [PDB: 6c3a, 6c3b, 6c3c, 6c3d] CMCF-ID Health
Heron, Paul W.; Abellán-Flos, Marta; Salmon, Laurent; Sygusch, Jurgen (2018). Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. Journal of Medicinal Chemistry 61(23) , 10558-10572. 10.1021/acs.jmedchem.8b01000. [PDB: 5tle, 5tlh, 5tlw, 5tlz] CMCF-BM, CMCF-ID Health
Hettle, Andrew G.; Vickers, Chelsea; Robb, Craig S.; Liu, Feng; Withers, Stephen G. et al. (2018). The Molecular Basis of Polysaccharide Sulfatase Activity and a Nomenclature for Catalytic Subsites in this Class of Enzyme. Structure 26(5) , 747-758.e4. 10.1016/j.str.2018.03.012. [PDB: 6b0k] CMCF-ID Health
Huang, Christine S.; Oberbeck, Nina; Hsiao, Yi-Chun; Liu, Peter; Johnson, Adam R. et al. (2018). Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity. Structure 26(5) , 767-777.e5. 10.1016/j.str.2018.04.002. [PDB: 5wni] CMCF-ID Health
Huguenin-Dezot, Nicolas; Alonzo, Diego A.; Heberlig, Graham W.; Mahesh, Mohan; Nguyen, Duy P. et al. (2018). Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid. Nature 565(7737) , 112-117. 10.1038/s41586-018-0781-z. [PDB: 6ecb, 6ecc, 6ece, 6ecf] CMCF-ID Health
Imkeller, Katharina; Scally, Stephen W.; Bosch, Alexandre; Martí, Gemma Pidelaserra; Costa, Giulia et al. (2018). Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope. Science 360(6395) , 1358-1362. 10.1126/science.aar5304. [PDB: 6d01, 6d11] CMCF-ID Health
Ishiyama, Noboru; Sarpal, Ritu; Wood, Megan N.; Barrick, Samantha K.; Nishikawa, Tadateru et al. (2018). Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions. Nature Communications 9(1) . 10.1038/s41467-018-07481-7. [PDB: 6duw, 6duy, 6dv1] CMCF-ID Health
Iyer, Janani S.; Zhu, Ning; Gasilov, Sergei; Ladak, Hanif M.; Agrawal, Sumit K. et al. (2018). Visualizing the 3D cytoarchitecture of the human cochlea in an intact temporal bone using synchrotron radiation phase contrast imaging. Biomedical Optics Express 9(8) , 3757-3767. 10.1364/boe.9.003757. BMIT-ID Health
Izadifar, Zahra; Babyn, Paul; Chapman, Dean (2018). Ultrasound Cavitation/Microbubble Detection and Medical Applications. Journal of Medical and Biological Engineering 39(3) , 259–276. 10.1007/s40846-018-0391-0. BMIT-BM Health
Jacques, Benoit; Coinçon, Mathieu; Sygusch, Jurgen (2018). Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases. Journal of Biological Chemistry 293(20) , 7737-7753. 10.1074/jbc.ra117.001098. [PDB: 5ucn, 5ucp, 5ucs, 5ucz, 5ud0, 5ud1, 5ud2] CMCF-BM, CMCF-ID Health
Jenkins, Meredith L.; Margaria, Jean Piero; Stariha, Jordan T. B.; Hoffmann, Reece M.; McPhail, Jacob A. et al. (2018). Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5. Nature Communications 9(1) . 10.1038/s41467-018-06196-z. [PDB: 6djl] CMCF-ID Health
Jha, Vikash; Ling, Hong (2018). Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender. Journal of Molecular Biology 430(11) , 1577-1589. 10.1016/j.jmb.2018.04.023. [PDB: 6brx, 6bs1] CMCF-ID Health
Kallander, Lara S.; Washburn, David; Hilfiker, Mark A.; Eidam, Hilary Schenck; Lawhorn, Brian G. et al. (2018). Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1. ACS Medicinal Chemistry Letters 9(7) , 736-740. 10.1021/acsmedchemlett.8b00173. [PDB: 6bsm] CMCF-ID Health