DONG, A.; DOMBROVSKI, L.; SMIL, D.; GETLIK, M.; BOLSHAN, Y. et al. (2015). Crystal structure of human WDR5 in complex with compound 9o. Protein Data Bank: 5eam. |
CMCF-ID |
PDB Deposition |
Health |
Blackler, Ryan J; Evans, Dylan W; Smith, David F; Cummings, Richard D; Brooks, Cory L et al. (2015). Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishesN-glycan phosphorylation in a branch-specific manner. Glycobiology 26(2) , 181-192. 10.1093/glycob/cwv093. [PDB: 4rzc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Eigenbrot, C.; Yu, C. (2015). EGFR kinase domain mutant "TMLR" with compound 30. Protein Data Bank: 5cap. |
CMCF-ID |
PDB Deposition |
Health |
Eigenbrot, C.; Yu, C. (2015). EGFR kinase domain mutant "TMLR" with compound 29. Protein Data Bank: 5cao. |
CMCF-ID |
PDB Deposition |
Health |
Eigenbrot, C.; Yu, C. (2015). EGFR kinase domain mutant "TMLR" with compound 24. Protein Data Bank: 5cal. |
CMCF-ID |
PDB Deposition |
Health |
Heald, Robert; Bowman, Krista K.; Bryan, Marian C.; Burdick, Daniel; Chan, Bryan et al. (2015). Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. Journal of Medicinal Chemistry 58(22) , 8877-8895. 10.1021/acs.jmedchem.5b01412. [PDB: 5cal, 5cao, 5cap] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Dutta, D.; Ravulapalli, R.; Merrill, A.R. (2015). C3larvin toxin, an ADP-ribosyltransferase from Paenibacillus larvae, Orthorhombic Form. Protein Data Bank: 5dzq. |
CMCF-ID |
PDB Deposition |
Health |
DONG, A.; ZHANG, Q.; TEMPEL, W.; Bountra, C.; Arrowsmith, C.H. et al. (2015). Crystal structure of the ROQ domain of human Roquin-2. Protein Data Bank: 4z30. |
CMCF-ID |
PDB Deposition |
Health |
Klein, D.J.; Patel, S. (2015). Crystal Structure of the Prototype Foamy Virus Intasome with a 2-Pyridinone Aminal Inhibitor. Protein Data Bank: 4ztf. |
CMCF-ID |
PDB Deposition |
Health |
Raheem, Izzat T.; Walji, Abbas M.; Klein, Daniel; Sanders, John M.; Powell, David A. et al. (2015). Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors. Journal of Medicinal Chemistry 58(20) , 8154-8165. 10.1021/acs.jmedchem.5b01037. [PDB: 4ztf] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Baker, P.; Little, D.J.; Howell, P.L. (2015). Structure of PslG from Pseudomonas aeruginosa in complex with mannose. Protein Data Bank: 5bxa. |
CMCF-ID |
PDB Deposition |
Health |
Ndubaku, Chudi O.; Crawford, James J.; Drobnick, Joy; Aliagas, Ignacio; Campbell, David et al. (2015). Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pKa Polar Moiety. ACS Medicinal Chemistry Letters 6(12) , 1241-1246. 10.1021/acsmedchemlett.5b00398. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Robb, Melissa; Robb, Craig S.; Higgins, Melanie A.; Hobbs, Joanne K.; Paton, James C. et al. (2015). A Second β-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans. Journal of Biological Chemistry 290(52) , 30888-30900. 10.1074/jbc.m115.688630. [PDB: 5a6a, 5a6b, 5a6k, 5ac5] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Baker, Perrin; Whitfield, Gregory B.; Hill, Preston J.; Little, Dustin J.; Pestrak, Matthew J. et al. (2015). Characterization of the Pseudomonas aeruginosa Glycoside Hydrolase PslG Reveals That Its Levels Are Critical for Psl Polysaccharide Biosynthesis and Biofilm Formation. Journal of Biological Chemistry 290(47) , 28374-28387. 10.1074/jbc.m115.674929. [PDB: 5bxa] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Gregg, Katie J.; Suits, Michael D.L.; Deng, Lehua; Vocadlo, David J.; Boraston, Alisdair B. et al. (2015). Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism. Journal of Biological Chemistry 290(42) , 25657-25669. 10.1074/jbc.m115.680470. |
CMCF-ID |
Peer-Reviewed Article |
Health |