Smirnova, Ekaterina; Kwan, Jamie J.; Siu, Ryan; Gao, Xin; Zoidl, Georg et al. (2016). A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein. Cell Communication and Signaling 14(1) , 17. 10.1186/s12964-016-0140-3. [PDB: 5l1m] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Solomonson, Matthew; Setiaputra, Dheva; Makepeace, Karl A.T.; Lameignere, Emilie; Petrotchenko, Evgeniy V. et al. (2015). Structure of EspB from the ESX-1 Type VII Secretion System and Insights into its Export Mechanism. Structure 23(3) , 571-583. 10.1016/j.str.2015.01.002. [PDB: 4wj1, 4wj2] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Bryson, Steve; Thomson, Christy A.; Risnes, Louise F.; Dasgupta, Somnath; Smith, Kenneth et al. (2016). Structures of Preferred Human IgV Genes–Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. Journal of Immunology 196(11) , 4723-4730. 10.4049/jimmunol.1402890. [PDB: 4hh9, 4hha] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Al-Dulaymi, Mays A.; Chitanda, Jackson M.; Mohammed-Saeid, Waleed; Araghi, Hessamaddin Younesi; Verrall, Ronald E. et al. (2016). Di-Peptide-Modified Gemini Surfactants as Gene Delivery Vectors: Exploring the Role of the Alkyl Tail in Their Physicochemical Behavior and Biological Activity. AAPS Journal 18(5) , 1168-1181. 10.1208/s12248-016-9906-1. |
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Peer-Reviewed Article |
Health |
ELFARNAWANY, M.; ALAM, S. RIYAHI; ROHANI, S.A.; ZHU, N.; AGRAWAL, S.K. et al. (2016). Micro-CT versus synchrotron radiation phase contrast imaging of human cochlea. Journal of Microscopy 265(3) , 349-357. 10.1111/jmi.12507. |
BMIT-ID |
Peer-Reviewed Article |
Health |
Watterson, Scott H.; De Lucca, George V.; Shi, Qing; Langevine, Charles M.; Liu, Qingjie et al. (2016). Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers. Journal of Medicinal Chemistry 59(19) , 9173-9200. 10.1021/acs.jmedchem.6b01088. [PDB: 5t18] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Richter, Jeremy M.; Cheney, Daniel L.; Bates, J. Alex; Wei, Anzhi; Luettgen, Joseph M. et al. (2016). Design and Synthesis of Novel Meta-Linked Phenylglycine Macrocyclic FVIIa Inhibitors. ACS Medicinal Chemistry Letters 8(1) , 67-72. 10.1021/acsmedchemlett.6b00375. [PDB: 5tqe] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Movahedin, Mohammadreza; Brooks, Teresa M; Supekar, Nitin T; Gokanapudi, Naveen; Boons, Geert-Jan et al. (2016). Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen. Glycobiology , 677-687. 10.1093/glycob/cww131. [PDB: 5t6p, 5t78] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Moustakim, Moses; Clark, Peter G. K.; Trulli, Laura; Fuentes de Arriba, Angel L.; Ehebauer, Matthias T. et al. (2016). Discovery of a PCAF Bromodomain Chemical Probe. Angewandte Chemie - International Edition 56(3) , 827-831. 10.1002/anie.201610816. [PDB: 5tpx] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Parker, Michelle L.; Houston, Simon; Wetherell, Charmaine; Cameron, Caroline E.; Boulanger, Martin J. et al. (2016). The Structure of Treponema pallidum Tp0624 Reveals a Modular Assembly of Divergently Functionalized and Previously Uncharacterized Domains. PLoS ONE 11(11) , e0166274. 10.1371/journal.pone.0166274. [PDB: 5jir] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Hewitt, Stephen Nakazawa; Dranow, David M.; Horst, Benjamin G.; Abendroth, Jan A.; Forte, Barbara et al. (2016). Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. ACS Infectious Diseases 3(1) , 34-44. 10.1021/acsinfecdis.6b00078. [PDB: 4wi1, 5ifu] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Crawford, Terry D.; Romero, F. Anthony; Lai, Kwong Wah; Tsui, Vickie; Taylor, Alexander M. et al. (2016). Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300. Journal of Medicinal Chemistry 59(23) , 10549-10563. 10.1021/acs.jmedchem.6b01022. [PDB: 5ktw] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Bloudoff, Kristjan; Fage, Christopher D.; Marahiel, Mohamed A.; Schmeing, T. Martin (2016). Structural and mutational analysis of the nonribosomal peptide synthetase heterocyclization domain provides insight into catalysis. Proceedings of the National Academy of Sciences of the United States of America 114(1) , 95-100. 10.1073/pnas.1614191114. [PDB: 5t3e] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Myers, Cullen L.; Li, Franco K.K.; Koo, Byoung-Mo; El-Halfawy, Omar M.; French, Shawn et al. (2016). Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component. Journal of Biological Chemistry 291(50) , 26066-26082. 10.1074/jbc.m116.760447. [PDB: 5t91, 5t9b, 5t9c] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
McGurn, Leah D.; Moazami-Goudarzi, Maryam; White, Sean A.; Suwal, Tannu; Brar, Beant et al. (2016). The structure, kinetics and interactions of the β-carboxysomal β-carbonic anhydrase, CcaA. Biochemical Journal 473(24) , 4559-4572. 10.1042/bcj20160773. [PDB: 5swc] |
CMCF-ID |
Peer-Reviewed Article |
Health |