Publication Beamlines Strategic Pillar
Mothersole, Robert G.; Kolesnikov, Maxim; Chan, Anson C. K.; Oduro, Emmanuella; Murphy, Michael E. P. et al. (2022). Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species. Biochemistry 61(13) , 1378-1391. 10.1021/acs.biochem.2c00197. [PDB: 8d27] CMCF-BM Health
Naidu, B. Narasimhulu; Patel, Manoj; McAuliffe, Brian; Ding, Bo; Cianci, Christopher et al. (2022). Design, Synthesis, and Preclinical Profiling of GSK3739936 (BMS-986180), an Allosteric Inhibitor of HIV-1 Integrase with Broad-Spectrum Activity toward 124/125 Polymorphs. Journal of Medicinal Chemistry 65(6) , 4949-4971. 10.1021/acs.jmedchem.1c02169. [PDB: 7t9o] CMCF-ID Health
Navas, Laura E.; Zahn, Michael; Bajwa, Harbir; Grigg, Jason C.; Wolf, Megan E. et al. (2022). Characterization of a phylogenetically distinct extradiol dioxygenase involved in the bacterial catabolism of lignin-derived aromatic compounds. Journal of Biological Chemistry 298(5) , 101871. 10.1016/j.jbc.2022.101871. [PDB: 7q2a] CMCF-BM Health
Newton, J.M.; Pushie, M.J.; Sylvain, N.J.; Hou, H.; Weese Maley, S. et al. (2022). Sex differences in the mouse photothrombotic stroke model investigated with X-ray fluorescence microscopy and Fourier transform infrared spectroscopic imaging. IBRO Neuroscience Reports 13, 127-135. 10.1016/j.ibneur.2022.07.006. MID-IR Health
Nguyen, Peter; Eshaque, Rony; Garland, Barbara Anne; Dang, Anthony; Suits, Michael D. L. et al. (2022). Degradation of chondroitin sulfate A by a PUL-like operon in Tannerella forsythia. PLoS ONE 17(9) , e0272904. 10.1371/journal.pone.0272904. [PDB: 8di0, 8di1] CMCF-BM, CMCF-ID Health
Parcella, Kyle; Wang, Tao; Eastman, Kyle; Zhang, Zhongxing; Yin, Zhiwei et al. (2022). Discovery and Preclinical Profiling of GSK3839919, a Potent HIV-1 Allosteric Integrase Inhibitor. ACS Medicinal Chemistry Letters 13(6) , 972-980. 10.1021/acsmedchemlett.2c00115. [PDB: 7uoq] CMCF-ID Health
Pollock, Georgina L.; Grishin, Andrey M.; Giogha, Cristina; Gan, Jiyao; Oates, Clare V. et al. (2022). Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli. Proceedings of the National Academy of Sciences of the United States of America 119(34) . 10.1073/pnas.2204332119. [PDB: 7tzk] CMCF-BM Health
Pushie, M J; Messmer, M; Sylvain, N J; Heppner, J; Newton, J M et al. (2022). Multimodal imaging of hemorrhagic transformation biomarkers in an ischemic stroke model.. Metallomics 14(4) . 10.1093/mtomcs/mfac007. MID-IR Health
Rasool, Shafqat; Veyron, Simon; Soya, Naoto; Eldeeb, Mohamed A.; Lukacs, Gergely L. et al. (2022). Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex. Molecular Cell 82(1) , 44-59. 10.1016/j.molcel.2021.11.012. CMCF-ID Health
Sharon, Itai; Grogg, Marcel; Hilvert, Donald; Schmeing, T. Martin (2022). The structure of cyanophycinase in complex with a cyanophycin degradation intermediate. Biochimica et Biophysica Acta - General Subjects 1866(11) , 130217. 10.1016/j.bbagen.2022.130217. [PDB: 7uqv] CMCF-BM Health
Sharon, Itai; Grogg, Marcel; Hilvert, Donald; Schmeing, T. Martin (2022). Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2. ACS Chemical Biology 17(3) . 10.1021/acschembio.1c01007. [PDB: 7ta5] CMCF-BM Health
Shen, Yao; Gomez-Blanco, Josue; Petassi, Michael T.; Peters, Joseph E.; Ortega, Joaquin et al. (2022). Structural basis for DNA targeting by the Tn7 transposon. Nature Structural and Molecular Biology 29(2) , 143-151. 10.1038/s41594-022-00724-8. [PDB: 7mbw] CMCF-BM Health
Stille, Julia K.; Tjutrins, Jevgenijs; Wang, Guanyu; Venegas, Felipe A.; Hennecker, Christopher et al. (2022). Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CLpro covalent inhibitors. European Journal of Medicinal Chemistry 229, 114046. 10.1016/j.ejmech.2021.114046. [PDB: 7mlf] CMCF-BM Health
Tao, Xuan; Zhang, Lu; Du, Liubing; Lu, Kai; Zhao, Zhennan et al. (2022). Inhibition of SARS-CoV-2 replication by zinc gluconate in combination with hinokitiol. Journal of Inorganic Biochemistry 231, 111777. 10.1016/j.jinorgbio.2022.111777. CMCF-ID Health
Taylor, Alexander M.; Bailey, Chris; Belmont, Lisa D.; Campbell, Robert; Cantone, Nico et al. (2022). GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1. Journal of Medicinal Chemistry 65(16) , 11177-11186. 10.1021/acs.jmedchem.2c00662. [PDB: 7td9] CMCF-ID Health