| Eigenbrot, C.; Yu, C. (2015). EGFR kinase (T790M/L858R) apo. Protein Data Bank: 5edp. |
CMCF-BM |
PDB Deposition |
Health |
| Eigenbrot, C.; Yu, C. (2015). EGFR kinase domain mutant "TMLR" with compound 30. Protein Data Bank: 5cap. |
CMCF-ID |
PDB Deposition |
Health |
| Eigenbrot, C.; Yu, C. (2015). EGFR kinase domain mutant "TMLR" with compound 29. Protein Data Bank: 5cao. |
CMCF-ID |
PDB Deposition |
Health |
| Eigenbrot, C.; Yu, C. (2015). EGFR kinase domain mutant "TMLR" with compound 24. Protein Data Bank: 5cal. |
CMCF-ID |
PDB Deposition |
Health |
| Gregg, Katie J.; Suits, Michael D.L.; Deng, Lehua; Vocadlo, David J.; Boraston, Alisdair B. et al. (2015). Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism. Journal of Biological Chemistry 290(42) , 25657-25669. 10.1074/jbc.m115.680470. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Heald, Robert; Bowman, Krista K.; Bryan, Marian C.; Burdick, Daniel; Chan, Bryan et al. (2015). Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. Journal of Medicinal Chemistry 58(22) , 8877-8895. 10.1021/acs.jmedchem.5b01412. [PDB: 5cal, 5cao, 5cap] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Klein, D.J.; Patel, S. (2015). Crystal Structure of the Prototype Foamy Virus Intasome with a 2-Pyridinone Aminal Inhibitor. Protein Data Bank: 4ztf. |
CMCF-ID |
PDB Deposition |
Health |
| Ndubaku, Chudi O.; Crawford, James J.; Drobnick, Joy; Aliagas, Ignacio; Campbell, David et al. (2015). Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pKa Polar Moiety. ACS Medicinal Chemistry Letters 6(12) , 1241-1246. 10.1021/acsmedchemlett.5b00398. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Parker, Michelle L.; Penarete-Vargas, Diana M.; Hamilton, Phineas T.; Guérin, Amandine; Dubey, Jitender P. et al. (2015). Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA–RON2 pair. Proceedings of the National Academy of Sciences of the United States of America 113(2) , 398-403. 10.1073/pnas.1515898113. [PDB: 4z80, 4z81] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Parker, M.L.; Boulanger, M.J. (2015). Crystal structure of AMA4 DI-DII-EGF1 from Toxoplasma gondii. Protein Data Bank: 4z81. |
CMCF-ID |
PDB Deposition |
Health |
| Parker, M.L.; Boulanger, M.J. (2015). Crystal structure of Toxoplasma gondii AMA4 DI-DII-EGF1 in complex with a 33 aa TgRON2L1 peptide. Protein Data Bank: 4z80. |
CMCF-ID |
PDB Deposition |
Health |
| Raheem, Izzat T.; Walji, Abbas M.; Klein, Daniel; Sanders, John M.; Powell, David A. et al. (2015). Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors. Journal of Medicinal Chemistry 58(20) , 8154-8165. 10.1021/acs.jmedchem.5b01037. [PDB: 4ztf] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ravulapalli, R.; Merrill, A.R. (2015). Crystal structure of ADP-ribosyltransferase Vis in complex with M6 Inhibitor. Protein Data Bank: 4yc0. |
CMCF-ID |
PDB Deposition |
Health |
| Ravulapalli, R.; Tempel, W.; Merrrill, A.R. (2015). Vis toxin, an ADP-ribosyltransferase from Vibrio Splendidus. Protein Data Bank: 4y1w. |
CMCF-ID |
PDB Deposition |
Health |
| Robb, Melissa; Robb, Craig S.; Higgins, Melanie A.; Hobbs, Joanne K.; Paton, James C. et al. (2015). A Second β-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans. Journal of Biological Chemistry 290(52) , 30888-30900. 10.1074/jbc.m115.688630. [PDB: 5a6a, 5a6b, 5a6k, 5ac5] |
CMCF-ID |
Peer-Reviewed Article |
Health |